Antisense oligonucleotides delivered into amniotic fluid improve spinal muscular atrophy in mice
Evidence is mounting that clinicians can treat serious genetic disorders prenatally by injecting medicine into the amniotic fluid, thus preventing […]
Research
May 20, 2025
For nonimmune hydrops, prenatal exome sequencing does better than gene panels
Our group has just published a paper comparing our experience with the diagnostic yield of exome sequencing with targeted gene […]
A new mechanism of maternal-fetal tolerance
Working in mice, the researchers have found that a recently discovered subset of cells in the immune system may prevent the mother’s immune system from attacking the placenta and fetus. If the research is confirmed in further animal studies, and the cells play a similar role in people, they could point the way toward new therapies for pregnancies that are threatened by defects in immune tolerance.