Research Fellowship in Fetal Diagnosis and Therapy

The fellowship is open to General Surgery Residents (PGY2+) & Obstetrics/Gynecology Fellows (PGY5+). Exceptional postdoctoral candidates from other fields, including Bioinformatics, will be considered.

One-year fellowship, potentially renewable for a second year.

None required, but some clinical opportunities may be available if desired.

The individual will be appointed as a research fellow through the Department of (Surgery/OBGYN). This is a fully funded position with benefits. Salary will be commensurate with training and experience.

To apply, please email the following material to Valerie Dougherty (dougherv@ucsf.edu), Program Manager for the Center for Maternal-Fetal Precision Medicine.

  • Curriculum Vitae
  • Personal Statement: 1-2 pages regarding your background, research interests as they relate to fetal diagnosis and therapy, and career aspirations
  • Contact information for three professional references

October 1, 2020

July 1, 2021

Projects undertaken during the fellowship will depend on the interests and experience of the fellow and may range from basic to translational to clinical research. The main areas of investigation are prenatal diagnosis, bioinformatics, and the development and implementation of new fetal molecular therapies (such as stem cell or gene therapy).

The Center for Maternal-Fetal Precision Medicine pursues an ambitious agenda to transform the field of maternal-fetal medicine. Research activities of the Center are organized around genetics, fetal immunology, and molecular therapies. We aim to:

Genetics

  • Develop accurate and rapid prenatal diagnosis strategies to determine genetic causes of fetal abnormalities
  • Determine the efficacy of exome sequencing and other molecular tests to find underlying genetic causes of non-immune hydrops fetalis
  • Identify disorders for which fetal therapeutic strategies show promise

Fetal immunology

  • Investigate the immune basis of preterm labor and various congenital anomalies
  • Identify opportunities to intervene during fetal development to improve the prognosis for a fetus

Molecular therapies

Develop molecular therapies to treat genetic disorders in the fetal environment, including:

  • Enzyme replacement therapy
  • Stem cell transplantation
  • Genetic therapies, including antisense oligonucleotides (ASOs), gene replacement, and CRISPR-based approaches

The fellow will work with a multi-disciplinary group of scientists and clinicians

Center Faculty

Collaborators

  • Vibrant training program with MD and PhD scientists working together to solve clinically relevant problems
  • Ample opportunities for professional development by participating in formal and informal lectures, symposia, and journal clubs
  • Multidisciplinary training in the collaborative environment at UCSF
  • Training in clinical research, including practical and regulatory aspects of starting and running clinical trials
  • Exposure to cutting-edge fetal diagnostics and therapies