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A new mechanism of maternal-fetal tolerance

Schematic depicting a proposed mechanism of the role of eTACs in maternal-fetal tolerance
Proposed mechanism of the role of eTACs in maternal-fetal tolerance. From Gillis-Buck et al. Sci Immunol. 2021 Jul 16; 6(61):eabf1968.

Working in mice, UCSF researchers have found that a recently discovered subset of cells in the immune system may prevent the mother’s immune system from attacking the placenta and fetus. (UCSF press release)

Article published in the Science Immunology,16 Jul 2021: Extrathymic Aire-expressing cells support maternal-fetal tolerance.