For nonimmune hydrops, prenatal exome sequencing does better than gene panels
Our group has just published a paper comparing our experience with the diagnostic yield of exome sequencing with targeted gene […]
News
September 15, 2021
A new mechanism of maternal-fetal tolerance
Working in mice, the researchers have found that a recently discovered subset of cells in the immune system may prevent the mother’s immune system from attacking the placenta and fetus. If the research is confirmed in further animal studies, and the cells play a similar role in people, they could point the way toward new therapies for pregnancies that are threatened by defects in immune tolerance.
Alpha Thalassemia Major: No Longer a Fatal Disease
Conference Archive On January 8-9, 2021, the Center for Maternal-Fetal Precision Medicine hosted an international, online conference on alpha thalassemia […]
Prenatal exome sequencing identifies genetic causes of non-immune hydrops fetalis
A new study led by Teresa Sparks, MD, MAS, an investigator in the Center for Maternal-Fetal Precision Medicine and Assistant […]
BrainVar catalogues genetic variants that underlie brain development – prenatally, postnatally, through childhood
Center investigator and Associate Professor of Psychiatry, Stephan Sanders, BMBS, PhD, and colleagues have developed a catalogue of genetic variants […]
Fetal molecular therapies show promise in studies of MPS7 mice
Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result […]
Fixing nature’s genetic mistakes in the womb
On November 18, 2019, we convened an In Utero Gene Therapy Think Tank in San Francisco to expand the discussion […]
Time Magazine covers clinical trial for alpha thalassemia major
Our Co-Founder, Tippi MacKenzie, MD, was featured in an article in Time Magazine discussing the alpha thalassemia major (ATM) clinical […]
Five Blood Transfusions, One Bone Marrow Transplant – All Before Birth (NYT)
The general goal of fetal therapy is to act early enough to minimize or even prevent lasting harm from severe […]
Medical breakthrough could save babies before birth
Dr. Tippi Mackenzie is an Associate Professor of Surgery at the University of California, San Francisco. Her lab’s recent research […]