Image of ultrasound

For nonimmune hydrops, prenatal exome sequencing does better than gene panels

Our group has just published a paper comparing our experience with the diagnostic yield of exome sequencing with targeted gene […]

September 15, 2021
Schematic depicting a proposed mechanism of the role of eTACs in maternal-fetal tolerance

A new mechanism of maternal-fetal tolerance

Working in mice, the researchers have found that a recently discovered subset of cells in the immune system may prevent the mother’s immune system from attacking the placenta and fetus. If the research is confirmed in further animal studies, and the cells play a similar role in people, they could point the way toward new therapies for pregnancies that are threatened by defects in immune tolerance.

July 27, 2021

Alpha Thalassemia Major: No Longer a Fatal Disease

Conference Archive On January 8-9, 2021, the Center for Maternal-Fetal Precision Medicine hosted an international, online conference on alpha thalassemia […]

January 8, 2021

Prenatal exome sequencing identifies genetic causes of non-immune hydrops fetalis

A new study led by Teresa Sparks, MD, MAS, an investigator in the Center for Maternal-Fetal Precision Medicine and Assistant […]

October 8, 2020
BrainVar Logo

BrainVar catalogues genetic variants that underlie brain development – prenatally, postnatally, through childhood

Center investigator and Associate Professor of Psychiatry, Stephan Sanders, BMBS, PhD, and colleagues have developed a catalogue of genetic variants […]

April 7, 2020
Photo of Green Glia Cells

Fetal molecular therapies show promise in studies of MPS7 mice

Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result […]

March 11, 2020
Photo of Tippi MacKenzie, MD, working

Fixing nature’s genetic mistakes in the womb

On November 18, 2019, we convened an In Utero Gene Therapy Think Tank in San Francisco to expand the discussion […]

December 11, 2019
Scientist working in lab

Time Magazine covers clinical trial for alpha thalassemia major

Our Co-Founder, Tippi MacKenzie, MD, was featured in an article in Time Magazine discussing the alpha thalassemia major (ATM) clinical […]

September 18, 2018
Photo of mother by baby

Five Blood Transfusions, One Bone Marrow Transplant – All Before Birth (NYT)

The general goal of fetal therapy is to act early enough to minimize or even prevent lasting harm from severe […]

May 25, 2018
Tippi MacKenzie

Medical breakthrough could save babies before birth

Dr. Tippi Mackenzie is an Associate Professor of Surgery at the University of California, San Francisco. Her lab’s recent research […]

January 30, 2018